Diacentrum – helping people with diabetes

Regimen changes

These derive from the causes that originate the disease. Above all, it is necessary to influence the causes of the disease – decreasing the amount of body fat (especially in the abdomen) and increasing physical activity. Therefore, to reduce the body weight.

If we expect that the reduction in weight will produce positive effects as to the control of the disease, specifically lowering the blood glucose concentrations (glycemia), we should achieve a decrease in weight of at least 5%. If our weight is for example 100 kg, we should reduce it by at least 5 kg so as to observe a visible improvement in the disease. In other words – we should have more exercise.

1. Medicaments   

If we have not managed to control the disease by regimen changes and the glucose concentrations in the blood stream keep above the normal levels, then it is time to take medicaments. It has been explained that there are two basic causes of the disease: insulin resistance and the impairment of beta-cells secretion.

Therefore, there are two basic groups of medicaments. Those in the first one attack insulin resistance, these are called insulin sensitisers. And the second ones increase insulin production, or, in other words, they force the pancreatic cells to increase their insulin production. These are called secretagogues.

Further on, there exists a supportive group of medicaments called the alpha glucosidase inhibitors which slow down glucose absorption. In the Czech Republic, there will be quite soon introduced two other medicament classes influencing the GLP 1 hormone and thus increasing insulin production. You can learn more in greater detail on another part of our website.

If a combination of the above mentioned medicaments proves to be insufficient to compensate diabetes, then insulin must be introduced.

The basic types of medicaments for Type 2 DM treatment